A strange case of healing Hodgkin lymphoma from SARS-CoV-2 virus has been presented in the UK. A 61-year-old man developed an anti-tumor response after getting infected with coronavirus despite being at an advanced stage of oncological disease.
A man was diagnosed with stage III classical Hodgkin lymphoma that affects the lymph nodes on either side or above the diaphragm and in the spleen.
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He was on haemodialysis for end-stage renal failure and had been without immunosuppressive therapy for three years after a failed kidney transplant. Needle biopsy of a supraclavicular node demonstrated Epstein–Barr virus (EBV)‐positive classical Hodgkin lymphoma.
Shortly after this diagnosis, he was also detected pneumonia caused by SARS-CoV-2 . After eleven days of palliative therapy, he was discharged to convalesce at home. Corticosteroids and immunotherapy were not administered.
Shortly after this diagnosis, he was also detected with pneumonia caused by SARS-CoV-2. After eleven days of care, he was discharged to convalesk at home. He was not given corticosteroid or immunochemotherapy.
Four months later, inflammation of the nodes had been reduced and an examination revealed widespread remission of lymphoma.
Four months later, palpable lymphadenopathy had reduced and scanning revealed a widespread remission of the lymphoma.
According to the hypothesis of the authors of the study published in the British Journal of Haematology, Sarah Challenor and David Tucker, the SARS-CoV-2 infection could have triggered an antitumor immune response thanks to the cytokines that are produced by the body to deal with the coronavirus.