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Diet That Makes You Obese, Diabetes And Alzheimer’s Patient

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Surprisingly, obese adults have a 55% greater risk of having depression, and diabetes will quadruple that risk.

New research suggests that fatty foods may not only make you fatter but also mess up your brain.

An international study led by the neuroscientists Professor Xin-Fu Zhou and Associate Professor Larisa Bobrovskaya at the University of South Australia has clearly linked the development of diabetes in mice fed a high-fat diet for 30 weeks to a decline in cognitive function, including anxiety, depression, and worsening Alzheimer’s disease.

Changes in the brain caused mice to have a slower metabolism, which made it more likely for them to gain too much weight.

Australian and Chinese researchers have reported their findings in Metabolic Brain Disease.

Associate Professor Larisa Bobrovskaya, a neurologist and biochemist at the University of South Australia, says the study adds to the growing body of evidence connecting diabetes and obesity with Alzheimer’s disease, which is expected to affect 100 million people worldwide by 2050.

Diabetes and obesity damage the central nervous system, aggravating mental illnesses and cognitive loss. 

“We demonstrated this in our study with mice,” said Assoc Prof Bobrovskaya.

In the experiment, mice were randomized to either a conventional diet or a high-fat diet for 30 weeks beginning at the age of eight weeks. At various intervals, blood sugar levels, body weight, glucose tolerance tests, and cognitive impairment were all evaluated.

In comparison to mice fed a standard diet, those on the high-fat diet put on a lot of weight, experienced insulin resistance, and began acting strangely.

When fed a high fat diet, genetically modified Alzheimer’s disease mice exhibited severe cognitive decline and pathological brain alterations.

“Obese individuals have about a 55 per cent increased risk of developing depression,” the professor added, “and diabetes will double that risk.”

“Our findings underline the importance of addressing the global obesity epidemic. A combination of obesity, age and diabetes is very likely to lead to a decline in cognitive abilities, Alzheimer’s disease and other mental health disorders,” the study authors concluded.

Image Credit: Getty

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