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How well your vaccine protects you against Delta variant?

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Aakash Molpariya
Aakash started in Nov 2018 as a writer at Revyuh.com. Since joining, as writer, he is mainly responsible for Software, Science, programming, system administration and the Technology ecosystem, but due to his versatility he is used for everything possible. He writes about topics ranging from AI to hardware to games, stands in front of and behind the camera, creates creative product images and much more. He is a trained IT systems engineer and has studied computer science. By the way, he is enthusiastic about his own small projects in game development, hardware-handicraft, digital art, gaming and music. Email: aakash (at) revyuh (dot) com

The delta variant of the coronavirus is spreading at breakneck speed. It is thought to be more contagious and could also make vaccinations less effective. Revyuh explains how well the various vaccines protect against the aggressive variant.

Delta is on the rise. 

More and more people are being immunized by vaccines. And experts also assume that the vaccines will continue to arm the immune system for a delta infection. 

However, initial studies show that the effectiveness is somewhat lower in all cases than against the wild types of Sars-CoV-2. 

This is especially true if only one dose of the respective vaccine has been administered. Revyuh will tell you how well the various vaccines protect against the Delta variant.


The effectiveness of the AstraZeneca vaccine had been examined by researchers from the British public health agency Public Health England (PHE). Accordingly, the protection against the delta variant should be around 60 per cent, provided that two vaccine doses have been administered. 

This means that the probability of symptomatic Covid 19 disease was lower in the vaccinated participants than among the unvaccinated.

For comparison: the study determined protection of 67 per cent for the alpha variant (B.1.1.7)

However, the AstraZeneca vaccine is also supposed to protect 92 per cent of the delta variant against severe courses.

Pfizer / BioNTech

How well the Pfizer / BioNTech vaccine protects against B.1.617.2 has been determined by scientists in a study that appeared in the journal “The Lancet” at the beginning of June. 

Their result: The double vaccination protects 88 per cent against asymptomatic Covid-19 disease triggered by Delta – with the alpha variant, which was previously known as the British variant, it is 93 per cent. 

However, according to the study, the Pfizer vaccine prevents hospital stays by 96 per cent even with the delta mutation.

Johnson & Johnson

So far, there is not enough data on the effectiveness against the delta variant for the vector vaccine from Johnson & Johnson. 

The vaccine was approved with a single dose and should guarantee the protection of around 65 per cent against Covid-19 symptoms. However, the vaccines against Delta are known to be less effective – especially if only one dose has been given.

Experts therefore suspect that people who have been vaccinated with the Johnson & Johnson vaccine may soon need a booster vaccination. 

For example, the US virologist Angela Rasmussen commented on Twitter and called for a booster vaccination if someone had been vaccinated with Johnson & Johnson for the first time. 

She herself received her first vaccination with the vaccine in April and therefore decided to have another vaccination with the vaccine from Biontech / Pfizer.


The US manufacturer Moderna published the first data on the effectiveness of its corona vaccine against the virus mutations on Tuesday. 

According to a communication from the company, there is a “slight reduction in the neutralizing titre” against the Delta, Gamma, Kappa and Eta variants. 

This refers to the neutralizing antibodies that can fight off and fight the virus in the body. In the case of Delta, this reduction is 2.1-fold compared to the original virus strain. The company does not state how effective it is against Delta.

The American immunologist Anthony Fauci, however, was optimistic: He told the Washington Post that he was assuming a similar level of protection as the Biontech / Pfizer vaccine. Both vaccines were ultimately based on mRNA technology.

First vaccination is probably not enough against delta mutation

Regardless of the vaccine, experts agree on one point: A single vaccination is probably not enough to provide comprehensive protection against the aggressive Delta variant.

The second vaccination is urgently needed in order to be able to ward off the mutants well.

According to experts:

The vaccination only provides complete protection if two vaccinations of the respective vaccine have been administered.

Accordingly, one should not rely on the initial protection. 

“In any case, it is not so easy to find very good immunity to pathogens that can be transmitted by the respiratory tract,” explained one infectiologist. 

We already know this from other pathogens, such as the real flu, influenza. 

“That’s why we need this second vaccination. It brings with it a booster of the initially initiated training for the immune system.”

It is all the more important that people get their second vaccination. 

And that those who have recovered who have already survived the infection are vaccinated. 

For these, however, single vaccination is initially sufficient. 

“You can imagine it that way,” explained the infectiologist, “the immune system was activated by the disease. The vaccination boosts it.”

Photo by Ben Hasty/MediaNews Group/Reading Eagle via Getty Images

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